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However, they are costly and time-consuming to conduct, motivating interest in predicting causal effects from existing experimental evidence. Recent advances in large language models (LLMs) have demonstrated strong performance on knowledge-intensive tasks, raising the question of whether these models can be used for forecasting causal effect sizes. To investigate this, we introduce Query2Effect, a new large-scale benchmark consisting of more than 72,000 natural language questions aligned with experiment descriptions, created to simulate realistic information-seeking scenarios by varying query specificity along dimensions of implicitness, abstraction, and ambiguity. We then propose a two-step framework that first generates a synthetic structured representation of a query before predicting effect size us","title":"Predicting Causal Effects from Natural Language Queries using Structured Representations","url":"https://arxiv.org/abs/2605.29631","vendor":"arxiv_cs_ai"},"summary":"arXiv:2605.29631v1 Announce Type: cross \nAbstract: Randomized controlled trials are a cornerstone of medicine and the social sciences as they enable reliable estimates of causal effects. However, they are costly and time-consuming to conduct, motivating interest in predicting causal effects from existing experimental evidence. Recent advances in large language models (LLMs) have demonstrated strong performance on knowledge-intensive tasks, raising the question of whether these models can be used for forecasting causal effect sizes. To investigate this, we introduce Query2Effect, a new large-scale benchmark consisting of more than 72,000 natural language questions aligned with experiment descriptions, created to simulate realistic information-seeking scenarios by varying query specificity along dimensions of implicitness, abstraction, and ambiguity. 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