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Because recovery, remodelling and degeneration of bones, joints and related tissues unfold over months to years, care requires longitudinal management rather than isolated decisions. Clinicians must repeatedly integrate evolving patient evidence, medical knowledge and stage-specific functional goals, yet evidence is often fragmented across visits, departments and hospital systems, disrupting continuous, individualised management. Here we report OrthoPilot, a clinical artificial intelligence (AI) system powered by a large language model (LLM) that integrates hospital data streams with authoritative external knowledge for continuous musculoskeletal care. It autonomously retrieves real-time imaging, laboratory, pathology and order data and translates evolving patient states into evidence-based decisions from admissi","title":"Evidence-Grounded AI for Musculoskeletal Care","url":"https://arxiv.org/abs/2607.12527","vendor":"arxiv_cs_ai"},"summary":"arXiv:2607.12527v3 Announce Type: replace \nAbstract: Musculoskeletal diseases are among the leading causes of disability and drive the greatest global need for rehabilitation. Because recovery, remodelling and degeneration of bones, joints and related tissues unfold over months to years, care requires longitudinal management rather than isolated decisions. Clinicians must repeatedly integrate evolving patient evidence, medical knowledge and stage-specific functional goals, yet evidence is often fragmented across visits, departments and hospital systems, disrupting continuous, individualised management. Here we report OrthoPilot, a clinical artificial intelligence (AI) system powered by a large language model (LLM) that integrates hospital data streams with authoritative external knowledge for continuous musculoskeletal care. It autonomously retrieves real-time imaging, laboratory, pathology and order data and translates evolving patient states into evidence-based decisions from admissi","title":"Evidence-Grounded AI for Musculoskeletal Care","vendor":"arxiv_cs_ai"},"confidence":{"method":"deterministic"},"decision":"POSITIVE","issued_at":"2026-07-22T04:43:18Z","notes":"Spider vendor_press (news) news.vendor_press.v1","object":{"captured_by":"crovia.spider.vendor_press","primary_source_url":"https://arxiv.org/abs/2607.12527"},"predecessors":[],"schema":"crovia.axiom.v1","signature":"ed25519:aeaf439b39ce121849aa2eacab316cf5bdf16f785005b453d0eb10affc0638f224da306d679beb34503580e794337bac2bebc317a96f38850be9c6d58357580f","signer":"crovia.substrate","subject":{"observed_at":"2026-07-22T04:43:18Z","source_collector":"spider:vendor_press","target_id":"https://arxiv.org/abs/2607.12527"},"tsa":{"authority":"crovia.substrate.bootstrap","rfc3161_token":"{\"kind\":\"crovia.bootstrap.tsa\",\"source_jsonl\":\"/opt/crovia/spider/data/news/vendor_press_v1.jsonl\",\"source_seal_merkle_root\":\"spider_vendor_press_v1\",\"upgrade_path\":\"Sessione H \\u2014 OpenTimestamps weekly anchor\"}"},"zk_mode":"clear","zk_proof":null},"ledger":{"leaf_hash":"10d4146afed5d2abf7056a13cbd45f2180f0e88f2aaabb8f7ab9458a64c886ea","leaf_index":340351,"ledger_path":"/opt/crovia/substrate/axiom_ledger.jsonl"},"merkle_proof":{"hash_alg":"sha256","leaf_prefix":"0x00","node_prefix":"0x01","odd_leaf_rule":"duplicate_last","path":[{"sibling":"ba0074b9312268b86742dd32b0ea309ce1acd0ff51ef30c5d7988707c169544b","side":"left"},{"sibling":"48b9b2890fab32b14ec446dc0d218e507c0330b91cf05b7c326f9a087c5c14dc","side":"left"},{"sibling":"4c07f61ad966808a3b146929259d0a9b91f74e3e93a998ee782c085ec99e180e","side":"left"},{"sibling":"aac6aa82d57c904dead75cbbed82a807ec1ebd89655aff2716a70f180119c175","side":"left"},{"sibling":"73133b61810a3e243788ab5dfc23f9954caa5b98e57b2fba966d44da125ccac7","side":"left"},{"sibling":"cb0ed9dbc614040ae574d9ceb6bce8dc8e1c6fb07bcc920e0ca7015465e607a5","side":"left"},{"sibling":"8802f296fb33ebb1f95ce56604f2c35b5365467e892c99b8d3e26d404adfa3df","side":"left"},{"sibling":"617d94b8a1da646ac45b4d986747eccb1604c294cb2a78b6cf4c70df505a76f4","side":"right"},{"sibling":"99d4b7aea5e7c917c580af0f1a9556bbd4d44f3f36cf9391892e7ef0340a8258","side":"left"},{"sibling":"c7fc9d4187cdc36f4c03b4b13daf4b880ea65536b051f71a5cc2543839d02697","side":"right"},{"sibling":"1758ec6ac206ce40e8368cb702195322fe3737d0fb03d8bd9e3b30acc4fa7d81","side":"right"},{"sibling":"0c407f0d553cf3fab8f9bd79205b8180e090cbf29fa0490ebb55155041ad5c86","side":"right"},{"sibling":"2dd9cb2521044ee7c6b74f2315e0a0253b8df0d04a7b810bbbbe7da5a9788769","side":"left"},{"sibling":"21d66dd41003813f710b7617944f1bfba3258658a5d3370c21cad8f9e945bc99","side":"left"},{"sibling":"787ee3744642ff909d610b0514cb100784f0ef1ba0ef4c70a0dc91f0ab2bb192","side":"right"},{"sibling":"9fc8a8ebbc1bff7e62b9f1e1c681c91e7196092ce9551573df6e23096df13e4d","side":"right"},{"sibling":"77025bcb374a7ad74f520643e20a8ae1205a7ee78507b0beb93117760f1c29d3","side":"left"},{"sibling":"ee6f33920899d9bdef2eb706dfff29e26eea61e29ea9824c6c8e6bcd48275d76","side":"right"},{"sibling":"1cecb7f447febd025aac272837c80de218aecc6485d2395a509b2a1f1b9c746e","side":"left"}]},"schema":"crovia.axiom_proof.v1","seal":{"first_collector_run_id":"","first_receipt_hash":"","jsonl_path":"/opt/crovia/substrate/axiom_ledger.jsonl","key_id":"430895f101d38164","last_collector_run_id":"","last_receipt_hash":"","leaf_count":340557,"merkle_root":"7d45d94f20b5bf82263df45b87749e19e06161972f25141dd573cc138d566338","public_key_hex":"cf742e26f75669dc673cb5c0786a1ae23ae8ca19c347317192ce40c28a7ff25c","run_id":"hourly_json_retrofit_20260722T053701Z","schema":"crovia.seal.v1","seal_family_version":"crovia-seal-family/1","seal_kind":"substrate_batch","sealed_at":"2026-07-22T05:38:39Z","sig_algorithm":"ed25519","signature":"812cb61e90d3582ba508db8515c4168bbf8ee1c6762885609049d012f680f8068f15c98b9accf2042047dcfc6a6fc3885820ee34b0be350846386f64f2591309","signer_version":"1.1.0"},"trust_root":{"key_id":"430895f101d38164","public_key_hex":"cf742e26f75669dc673cb5c0786a1ae23ae8ca19c347317192ce40c28a7ff25c","signature_algorithm":"ed25519","url":"/registry/canon/TRUST_ROOT.md"},"verifier":{"spec":"/registry/canon/AXIOM_RECEIPT_v1.md","url":"/v/axm_3400eb2ca1922c19ea1ed9792fa100568d3aa96e968552bc44896450f0c19948"}}