{"_canonicalization":{"envelope_id":"axm_ + sha256(envelope minus {signature, axiom_id, anchors})","envelope_signature":"ed25519(envelope minus {signature, axiom_id})","json":"sort_keys=True, separators=(',',':'), ensure_ascii=False, allow_nan=False, utf-8","leaf_hash":"sha256(0x00 || canonical_json(envelope_full))","seal_signature":"ed25519(seal minus {signature, sig_algorithm})"},"axiom_id":"axm_93c458e1dde616cefa495dc3728c73b40e8e58320a8e2c49d5f080eaf193bf08","bitcoin_anchor":{"bitcoin_attestations":["bitcoin_block_949451"],"calendar_attestations":["https://finney.calendar.eternitywall.com","https://btc.calendar.catallaxy.com","https://alice.btc.calendar.opentimestamps.org","https://bob.btc.calendar.opentimestamps.org"],"ots_url":"/registry/data/substrate/anchors/77fc9c28fae777b81da5b495b3115474df6592dfac590333213d3bdf8b94a9b3.ots","stamped_at":"2026-05-15T03:00:03Z","status":"bitcoin"},"envelope":{"anchors":[{"chain":"crovia.axiom_graph","height":0,"merkle_proof":"spider_vendor_press_v1","root_at_anchor":"spider_vendor_press_v1"}],"axiom_id":"axm_93c458e1dde616cefa495dc3728c73b40e8e58320a8e2c49d5f080eaf193bf08","axiom_type":"AX.OBS","body":{"axiom_subtype":"news.vendor_press.v1","category":"news","fingerprint":"6aab86b1d72d9443cdedfd3ccb3cb4d78d02477f57f4bc0486be6c6010cbc009","published":"Wed, 06 May 2026 00:00:00 -0400","receipt_hash":"6aab86b1d72d9443cdedfd3ccb3cb4d78d02477f57f4bc0486be6c6010cbc009","schema":"spider.news.vendor_press.v1","spider":"vendor_press","spider_record":{"axiom_subtype":"news.vendor_press.v1","category":"news","decision_hint":"POSITIVE","envelope_target":"AX.OBS","fingerprint":"6aab86b1d72d9443cdedfd3ccb3cb4d78d02477f57f4bc0486be6c6010cbc009","observed_at":"2026-05-06T04:43:18.518819Z","parent_run_hash":"184209fc0f2ebdc4b721e1a74f74ab17637dab3344682b6e6bd1f3e5e8f2cd00","published":"Wed, 06 May 2026 00:00:00 -0400","runtime_version":"0.1.0","schema":"spider.news.vendor_press.v1","source_status":200,"source_url":"https://export.arxiv.org/rss/cs.AI","spider":"vendor_press","summary_excerpt":"arXiv:2605.02740v1 Announce Type: new \nAbstract: Evidence derived from large-scale real-world data (RWD) is increasingly informing regulatory evaluation and healthcare decision-making. Administrative claims provide population-scale, longitudinal records of healthcare utilization, expenditure, and detailed coding of diagnoses, procedures, and medications, yet their potential as a substrate for healthcare foundation models remains largely unexplored. Here we present ReClaim, a generative transformer trained from scratch on 43.8 billion medical events from more than 200 million enrollees in the MarketScan claims data spanning 2008-2022. ReClaim models longitudinal trajectories across diagnoses, procedures, medications, and expenditure, and was scaled to 140 million, 700 million, and 1.7 billion parameters. Across over 1,000 disease-onset prediction tasks, ReClaim achieved a mean AUC of 75.6%, substantially outperforming disease-specific LightGBM (66.3%) and the transformer-based Delphi mo","title":"Foundation Models to Unlock Real-World Evidence from Nationwide Medical Claims","url":"https://arxiv.org/abs/2605.02740","vendor":"arxiv_cs_ai"},"summary":"arXiv:2605.02740v1 Announce Type: new \nAbstract: Evidence derived from large-scale real-world data (RWD) is increasingly informing regulatory evaluation and healthcare decision-making. Administrative claims provide population-scale, longitudinal records of healthcare utilization, expenditure, and detailed coding of diagnoses, procedures, and medications, yet their potential as a substrate for healthcare foundation models remains largely unexplored. Here we present ReClaim, a generative transformer trained from scratch on 43.8 billion medical events from more than 200 million enrollees in the MarketScan claims data spanning 2008-2022. ReClaim models longitudinal trajectories across diagnoses, procedures, medications, and expenditure, and was scaled to 140 million, 700 million, and 1.7 billion parameters. Across over 1,000 disease-onset prediction tasks, ReClaim achieved a mean AUC of 75.6%, substantially outperforming disease-specific LightGBM (66.3%) and the transformer-based Delphi mo","title":"Foundation Models to Unlock Real-World Evidence from Nationwide Medical Claims","vendor":"arxiv_cs_ai"},"confidence":{"method":"deterministic"},"decision":"POSITIVE","issued_at":"2026-05-06T04:43:18Z","notes":"Spider vendor_press (news) news.vendor_press.v1","object":{"captured_by":"crovia.spider.vendor_press","primary_source_url":"https://arxiv.org/abs/2605.02740"},"predecessors":[],"schema":"crovia.axiom.v1","signature":"ed25519:0e10c7f1e143c912869478f40fe037b2392f6236971850a6ab3ef2ce67a8327bb76c99bc3014e9aabcd9136285c8fd94f719cb489424a5c927cba7e419b3cc01","signer":"crovia.substrate","subject":{"observed_at":"2026-05-06T04:43:18Z","source_collector":"spider:vendor_press","target_id":"https://arxiv.org/abs/2605.02740"},"tsa":{"authority":"crovia.substrate.bootstrap","rfc3161_token":"{\"kind\":\"crovia.bootstrap.tsa\",\"source_jsonl\":\"/opt/crovia/spider/data/news/vendor_press_v1.jsonl\",\"source_seal_merkle_root\":\"spider_vendor_press_v1\",\"upgrade_path\":\"Sessione H \\u2014 OpenTimestamps weekly anchor\"}"},"zk_mode":"clear","zk_proof":null},"ledger":{"leaf_hash":"05e8510ef36fb4976a1d9758c0a9a88448574be602282432f176f888df12cd30","leaf_index":116130,"ledger_path":"/opt/crovia/substrate/axiom_ledger.jsonl"},"merkle_proof":{"hash_alg":"sha256","leaf_prefix":"0x00","node_prefix":"0x01","odd_leaf_rule":"duplicate_last","path":[{"sibling":"523a4a385daa11a754a604ccd8ffe2dc8a88a53f4e7c6e7de7b44bcd6c68433b","side":"right"},{"sibling":"c0b120e39603c0de714756a43199f25a4401cb22b4ad0cdb7584175726c7aa3d","side":"left"},{"sibling":"4beeb2479a3eebcc1df590d51fd61a2f2f3322cf21de0fff0f3c0bb16787c0f9","side":"right"},{"sibling":"cf4466e75dca56ede993d6d2d3f039dfd33d44a0b894e17bb5483fc7ebd50130","side":"right"},{"sibling":"b6e2c2abe135f04f96ba355e6f1a307c58353379316cce63a1fae2c1755d762f","side":"right"},{"sibling":"5a5bd5088488c2d841e5644bb87aa3f88a65f213d4ac28f126df326c9ace510a","side":"left"},{"sibling":"bd77ee87eadee2f56aa2d552e85ba1e9254305d1b110792465e11c42048ac612","side":"right"},{"sibling":"337e888c904278e2dba91f3f1f4ea3c78aa6421dad9d2b8e076ce153c74c3f82","side":"left"},{"sibling":"aece872b65a68d3775a2636761a78e8ecbdc28b94538a659e6069c57bef430e0","side":"left"},{"sibling":"fb3602a0ad8c9fcab7b18e13690c40ca4a2f5402557d976d681a369555c04ae2","side":"right"},{"sibling":"ddc060ac400459417799f688c75d5b271636afa40d89ec7fc98652473a8061f6","side":"left"},{"sibling":"282afa51266e47629e34d808a360bbb276348bcc5a24bdcc93e83a76e580293e","side":"right"},{"sibling":"05f89b32c00462e60adf95c1fe4579cdc2791b36e8b17573d8f3b5fd5da95a0b","side":"right"},{"sibling":"8ccd9937a2c0d5c04044d07d1557791b7d07bb31eac41a39a675608d44b38f23","side":"right"},{"sibling":"3a5e69cf0803f4c91f3895ed7c9a95748fef240bec4422e167c05300f79f06c0","side":"left"},{"sibling":"f2817ab288b5324fe49770372c7a10f33f7cd11005f8d4c0a730316f5229dc98","side":"left"},{"sibling":"725fac972e772ca0dc598810ea1abc70df472f72d2d6ab8a0baee2b80e5d2f4c","side":"left"},{"sibling":"98fc57dfef8873b512edc8340f7181df57302bb96777625e072235c62d7c5895","side":"right"}]},"schema":"crovia.axiom_proof.v1","seal":{"first_collector_run_id":"","first_receipt_hash":"","jsonl_path":"/opt/crovia/substrate/axiom_ledger.jsonl","key_id":"430895f101d38164","last_collector_run_id":"","last_receipt_hash":"","leaf_count":134292,"merkle_root":"77fc9c28fae777b81da5b495b3115474df6592dfac590333213d3bdf8b94a9b3","public_key_hex":"cf742e26f75669dc673cb5c0786a1ae23ae8ca19c347317192ce40c28a7ff25c","run_id":"hourly_json_retrofit_20260515T023701Z","schema":"crovia.seal.v1","seal_family_version":"crovia-seal-family/1","seal_kind":"substrate_batch","sealed_at":"2026-05-15T02:37:25Z","sig_algorithm":"ed25519","signature":"68107a834b00b24f5d4501e5ec727445311f132a486567ecc4c72a4e6dff24c8c21f2de3105293353ba5fdbe370d032819af6aa70f694e2e39b6af6737507009","signer_version":"1.1.0"},"trust_root":{"key_id":"430895f101d38164","public_key_hex":"cf742e26f75669dc673cb5c0786a1ae23ae8ca19c347317192ce40c28a7ff25c","signature_algorithm":"ed25519","url":"/registry/canon/TRUST_ROOT.md"},"verifier":{"spec":"/registry/canon/AXIOM_RECEIPT_v1.md","url":"/v/axm_93c458e1dde616cefa495dc3728c73b40e8e58320a8e2c49d5f080eaf193bf08"}}