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Unfortunately, this training paradigm suffers from a key issue, named cross-task interference, due to conflicting gradients over shared parameters among different tasks. Some previous methods mitigate this issue by isolating task-specific parameters, e.g., task-specific neuron selection and mixture-of-experts. In this paper, we empirically reveal that the cross-task interference still exists for the existing solutions because of many parameters also shared by different tasks, and accordingly, we propose a novel solution, namely Basic Abilities Decomposition for multi-task Instruct-Tuning (BADIT). Specifically, we empirically find that certain parameters are consistently co-activated, and that co-activated parameters naturally organize into base groups. 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