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Although massive amounts of prior knowledge are available, and contain valuable causal information, effectively integrating this knowledge into the causal discovery process remains an open problem. We introduce CausalSTeward (CAST), a novel human-in-the-loop framework for interactively assembling large causal models. CausalSteward is a multi-agent collaborative system that tackles high-dimensional causality through a divide-and-conquer approach where large clusters of variables are iteratively partitioned and then separately analyzed. Our framework fuses prior knowledge with a data-driven approach by using tailored tools such as retrieval augmented generation and conditional independence tests. 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