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For many downstream tasks, however, the clinically meaningful unit is not a single CUI but a concept set comprising related synonyms, subtypes, and associated concepts. Constructing these sets is labour-intensive, inconsistently performed, and poorly supported by existing tools. Methods We present CUICurate, a graph-based retrieval-augmented generation (GraphRAG) framework for automated UMLS concept set curation. A UMLS knowledge graph (KG) was constructed and embedded for semantic retrieval. Candidate CUIs were retrieved using graph-based expansion and then filtered and classified using large language models (GPT-5 and Qwen3-32B). The framework was evaluated on five lexically heterogeneous clinical concepts against a manually curated concept sets and gold-standard concept sets.","title":"CUICurate: A GraphRAG-based Framework for Automated Clinical Concept Curation for NLP applications","url":"https://arxiv.org/abs/2602.17949","vendor":"arxiv_cs_ai"},"summary":"arXiv:2602.17949v2 Announce Type: replace-cross \nAbstract: Background: Clinical named entity recognition tools commonly map free text to Unified Medical Language System (UMLS) Concept Unique Identifiers (CUIs). For many downstream tasks, however, the clinically meaningful unit is not a single CUI but a concept set comprising related synonyms, subtypes, and associated concepts. Constructing these sets is labour-intensive, inconsistently performed, and poorly supported by existing tools. Methods We present CUICurate, a graph-based retrieval-augmented generation (GraphRAG) framework for automated UMLS concept set curation. A UMLS knowledge graph (KG) was constructed and embedded for semantic retrieval. Candidate CUIs were retrieved using graph-based expansion and then filtered and classified using large language models (GPT-5 and Qwen3-32B). The framework was evaluated on five lexically heterogeneous clinical concepts against a manually curated concept sets and gold-standard concept sets.","title":"CUICurate: A GraphRAG-based Framework for Automated Clinical Concept Curation for NLP applications","vendor":"arxiv_cs_ai"},"confidence":{"method":"deterministic"},"decision":"POSITIVE","issued_at":"2026-05-15T04:43:17Z","notes":"Spider vendor_press (news) news.vendor_press.v1","object":{"captured_by":"crovia.spider.vendor_press","primary_source_url":"https://arxiv.org/abs/2602.17949"},"predecessors":[],"schema":"crovia.axiom.v1","signature":"ed25519:d3987aeaa779e8f25526e7fe7837c66d810ffe3792943bfa274e39947f395a141c47cc271568a014cf9d77e077d61d9e5fc05d663b5e6b62c991947b2aaad002","signer":"crovia.substrate","subject":{"observed_at":"2026-05-15T04:43:17Z","source_collector":"spider:vendor_press","target_id":"https://arxiv.org/abs/2602.17949"},"tsa":{"authority":"crovia.substrate.bootstrap","rfc3161_token":"{\"kind\":\"crovia.bootstrap.tsa\",\"source_jsonl\":\"/opt/crovia/spider/data/news/vendor_press_v1.jsonl\",\"source_seal_merkle_root\":\"spider_vendor_press_v1\",\"upgrade_path\":\"Sessione H \\u2014 OpenTimestamps weekly anchor\"}"},"zk_mode":"clear","zk_proof":null},"ledger":{"leaf_hash":"61e6c28826a1d5128eaeec8c0f8b762cc38444de6ec2038f5f6ffa72c36ec1fb","leaf_index":134774,"ledger_path":"/opt/crovia/substrate/axiom_ledger.jsonl"},"merkle_proof":{"hash_alg":"sha256","leaf_prefix":"0x00","node_prefix":"0x01","odd_leaf_rule":"duplicate_last","path":[{"sibling":"7d08c64af0b4e4286b0b422ba55ec4f70d13b064e9bb579e98e57fcdee085b22","side":"right"},{"sibling":"5d4a6e16da6c5309e9aa98015eb754b736941af6f575ab40195b95e164bee386","side":"left"},{"sibling":"8e37515c762220c29ccd140eee7acdd1233890c8ed6a1190a11ee4ef4fea422d","side":"left"},{"sibling":"cfe1fbbaf9ee8a3e99a75f4253419fe01a772df4cbee2f354b2093881ceeb077","side":"right"},{"sibling":"c36d1229c95a999aa6441135705fd15d2b30eca6083ce6b83f5a334666414b5c","side":"left"},{"sibling":"952bb2ea9b8e1bb4f01c53d0e4d6522140e49683ac624344442d5a1522d7c3be","side":"left"},{"sibling":"4999a953ceed25471a2bccd6eadce4cee20773995bf2d506b76320a8705da9a4","side":"left"},{"sibling":"d8ac22bfe982d5dc7f00879b0b1dfae8f4e95a38a6242933cbebb3b7271d5704","side":"right"},{"sibling":"a17a0eaa87574a308e2c02cf125072b9e69566b9e8d6d2e64a02880192b885d5","side":"right"},{"sibling":"6bd0475fd3a73322a4f73095c96b072de89e462ce5839161aa552e0208619bce","side":"left"},{"sibling":"36672459e5ed50c64ee1842b69cb6d2eb682c2a04844555be8d124257571994a","side":"left"},{"sibling":"727783827652adfa99c455bd80a01bfb33836228e51068b4f654ef3da468ca69","side":"left"},{"sibling":"623194cd30880ed223e306737fdb111aa0d781751bfc47553c404a6af6aad2c4","side":"right"},{"sibling":"fc8f53ed42756907fb79ee19a4ed09f72c560e5302b3d98198b96bf1da635a4a","side":"right"},{"sibling":"d6607539da7ba39ec68be2d12f27ed6768766c745e3120fd915f88c5e288e07c","side":"right"},{"sibling":"b63408a424d27cd6a75e0fb155e69a58a328f41e9cb9dba1eddef9a5289cc7fd","side":"right"},{"sibling":"356fb36a4e188f03d7a05c54cd8789bdd40eda454b9bc9560f667acc08e6c4e0","side":"right"},{"sibling":"d841ad93efda0869e5eb97678f348f03f5caab4353e05ff4bf18f47fb945b822","side":"left"}]},"schema":"crovia.axiom_proof.v1","seal":{"first_collector_run_id":"","first_receipt_hash":"","jsonl_path":"/opt/crovia/substrate/axiom_ledger.jsonl","key_id":"430895f101d38164","last_collector_run_id":"","last_receipt_hash":"","leaf_count":134886,"merkle_root":"c6c7ae28c065bced89e7f844216b073f1a7cc4b378db0d41a98bcd21b28066db","public_key_hex":"cf742e26f75669dc673cb5c0786a1ae23ae8ca19c347317192ce40c28a7ff25c","run_id":"hourly_json_retrofit_20260515T053701Z","schema":"crovia.seal.v1","seal_family_version":"crovia-seal-family/1","seal_kind":"substrate_batch","sealed_at":"2026-05-15T05:37:26Z","sig_algorithm":"ed25519","signature":"5a3978c26017daf4104adbb3e1c3099c5750157acbfc7242ece1815dc6740fe08a690291ce0afe42011e20cc565b5ebe64ec016bf658b5bab563a63337985c05","signer_version":"1.1.0"},"trust_root":{"key_id":"430895f101d38164","public_key_hex":"cf742e26f75669dc673cb5c0786a1ae23ae8ca19c347317192ce40c28a7ff25c","signature_algorithm":"ed25519","url":"/registry/canon/TRUST_ROOT.md"},"verifier":{"spec":"/registry/canon/AXIOM_RECEIPT_v1.md","url":"/v/axm_c4d56ef6d39b555d577303dbbc92097326ebf5e239f4809d6f7264e738a8d904"}}